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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
12.12
Human Site:
S343
Identified Species:
20.51
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
S343
A
T
A
N
R
L
R
S
A
A
E
P
V
A
S
Chimpanzee
Pan troglodytes
XP_515128
385
44007
E312
D
R
E
R
R
E
H
E
R
E
E
R
M
G
Q
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
P245
E
V
L
C
K
G
Y
P
S
E
F
A
T
Y
L
Dog
Lupus familis
XP_850168
416
47320
S343
A
T
A
N
R
L
R
S
A
A
E
P
T
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
S343
A
T
A
N
R
L
R
S
A
A
E
P
V
A
S
Rat
Rattus norvegicus
P97633
325
37477
P253
E
V
L
C
K
G
F
P
A
E
F
A
M
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
N343
A
T
G
N
R
L
R
N
V
A
E
P
M
A
S
Frog
Xenopus laevis
Q5BP74
415
47421
G336
T
A
S
G
R
L
R
G
T
Q
E
V
T
P
S
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
T336
A
S
G
R
P
R
P
T
Q
D
G
A
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
N343
Q
Q
Q
Q
H
K
V
N
A
A
L
G
G
G
G
Honey Bee
Apis mellifera
XP_395574
413
47530
P334
D
Q
E
H
R
S
R
P
Y
T
R
Q
C
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
R343
T
A
A
T
V
R
L
R
N
Q
E
P
A
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S361
N
I
S
N
Q
P
T
S
S
S
A
R
D
S
M
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
P359
K
N
E
D
K
H
N
P
S
P
E
E
I
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
13.3
0
93.3
N.A.
100
6.6
N.A.
N.A.
73.3
33.3
6.6
N.A.
13.3
13.3
N.A.
26.6
P-Site Similarity:
100
20
13.3
93.3
N.A.
100
20
N.A.
N.A.
86.6
40
26.6
N.A.
20
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
15
29
0
0
0
0
0
36
36
8
22
8
36
8
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
15
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
15
0
22
0
0
8
0
8
0
22
58
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
15
8
0
15
0
8
0
0
8
8
8
15
8
% G
% His:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
22
8
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
15
0
0
36
8
0
0
0
8
0
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
8
% M
% Asn:
8
8
0
36
0
0
8
15
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
8
29
0
8
0
36
8
15
0
% P
% Gln:
8
15
8
8
8
0
0
0
8
15
0
8
0
0
15
% Q
% Arg:
0
8
0
15
50
15
43
8
8
0
8
15
0
0
0
% R
% Ser:
0
8
15
0
0
8
0
29
22
8
0
0
0
8
36
% S
% Thr:
15
29
0
8
0
0
8
8
8
8
0
0
22
0
8
% T
% Val:
0
15
0
0
8
0
8
0
8
0
0
8
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _